As the Los Angeles Rams gear up for a pivotal Week 3 matchup against the San Francisco 49ers, they have released their first injury report, bringing to light some significant concerns that could influence their game strategy. The latest injury report reveals some notable absences that loom large for the Rams.

The San Francisco 49ers officially have a significant injury problem on their hands. Running back Christian McCaffrey is out for at least three more weeks while he tends to his Achilles tendinitis. His absence already made things more difficult for the 49ers' offense.

The 49ers offense will look so much different without Christian McCaffrey and Deebo Samuel. Enter rookie wide receiver Jacob Cowing. Cowing ran a 4.38 40-yard dash at the Combine in March, so he's the fastest receiver on the team.