Nestled in the foothills of the Appalachian Mountains, Burton is an unincorporated community in Wetzel County, West Virginia, United States, located on a stretch of highway where both WV Route 7 and US Route 250 join for a few short miles between Cottontown and Hundred. These two roads are responsible for the majority of traffic to and from the ar…Nestled in the foothills of the Appalachian Mountains, Burton is an unincorporated community in Wetzel County, West Virginia, United States, located on a stretch of highway where both WV Route 7 and US Route 250 join for a few short miles between Cottontown and Hundred. These two roads are responsible for the majority of traffic to and from the area and provide important connections to New Martinsville to the west ; Fairmont to the southeast ; Morgantown, to the west ; and Moundsville to the northeast. Other important connections include WV Route 69 North into Pennsylvania, where it becomes PA Route 18 and leads towards Waynesburg and beyond to Pittsburgh. Pittsburgh International Airport, is the nearest intercontinental airport, while Burton is also served by a smaller regional airport, Morgantown Municipal Airport.