De Soto is a city in Sumter County, Georgia, United States. The population was 214 at the 2000 census. It is part of the Americus micropolitan st…De Soto is a city in Sumter County, Georgia, United States. The population was 214 at the 2000 census. It is part of the Americus micropolitan statistical area. The Georgia General Assembly incorporated the place in 1889 as the "Town of De Soto". The community is named for Hernando de Soto, the explorer who discovered the Mississippi River.
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